Reverb Therapeutic’s novel antibody-based Amplify•R platform combines bispecific antibody engineering with data-driven modelling of antibody interactions to amplify and redirect endogenous cytokines to tissues of interest. By redirecting the body’s naturally occurring cytokines, this approach avoids the hurdles seen in other treatments using lab-produced cytokines, such as systemic exposure to other parts of the body or immunogenicity — a provoked immune response to a foreign substance.  

“We are excited to have the backing of this standout group of investors as we advance the Amplify•R platform. The Amplify•R platform has broad potential across many cytokines. With this funding, we will take our lead IL-15 bispecific program to the candidate stage and will develop additional bispecific programs spanning other cytokines and additional cellular targets.” 

— David de Graaf, Ph.D, CEO of Reverb Therapeutics 

Reverb’s technology is presenting an exciting potential treatment for a broad range of diseases. Preclinical studies have established the platform’s ability to redirect cytokines and shrink tumours, and the company’s initial focus will be on the treatment of cancer and autoimmune diseases. With this investment, it will continue to advance its therapeutics well as develop additional programs. 

InBC invested in Reverb Therapeutics alongside other investors. This investment is working in parallel with the B.C. Life Sciences and Biomanufacturing Strategy to support a key growth sector in B.C., including supporting the growth and retention of research and development and intellectual property in the province. British Columbia is currently home to the fastest growing life sciences sector in Canada, employing over 20,000 people. 

Are you a company with strong connections to B.C. and ready to scale? InBC is making equity investments in growing, innovative private companies. Learn more and connect today

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To continue growing our investing capacity and the number of investors in the province, we have also invested into additional venture funds. These funds are committed to investing in B.C.-based companies and specialize in specific sectors to support companies across various stages of growth in their respective industries.

4AG Robotics

InBC has invested $4 million into 4AG Robotics, an agritech company which develops and builds leading robotics solutions for agriculture producers to grow sustainably. 4AG’s harvesting robot is helping mushroom farmers to improve their yields and increase operational efficiencies, while addressing labour challenges and reducing food waste in the agriculture sector. Learn more

Clarius Mobile Health

InBC has invested $5 million into Clarius Mobile Health Corp., producers of wireless handheld ultrasound scanners enabling healthcare practitioners to manage and perform exams from anywhere. Clarius is improving patient outcomes and accessibility to care with scanners that are affordable, ultra-portable and using artificial intelligence to deliver accurate and high-definition imaging. Learn more

Amplitude Ventures

InBC has invested $10 million into Amplitude Ventures Fund II, a venture fund that will invest in life sciences and biotechnology companies, bringing healthcare innovations to market to help improve the lives of patients. Amplitude’s Fund II will invest in early-stage companies in the areas of high-value therapies, medical technology, and artificial intelligence and machine learning. Learn more

Pender Ventures

InBC has invested $10 million into the Pender Technology Inflection Fund II, a venture fund investing in healthtech and B2B technology startups to drive efficiencies and improve clinical decision-making, patient outcomes and healthcare operations. Pender’s Fund II is focusing on companies at the growth stages between commercialization and scale up. Learn more

InBC’s investments are working in parallel with the province’s Stronger BC Economic Plan to accomplish inclusive and clean growth over the long term, including the strategic growth of sectors playing a significant role in the B.C. economy, such as agritech, life sciences and biomanufacturing. These investments are driving innovation, creating quality jobs, increasing research and development spend, and retaining intellectual property in the province.

We are currently investing in growing, innovative companies looking for an equity investment. Are you a company fundraising a Series A or later round? Consider InBC as an investor by learning more and expressing your interest here.

Read the press release

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